My WebLink
|
Help
|
About
|
Sign Out
Home
Browse
Search
06/16/2015 (2)
CBCC
>
Meetings
>
2010's
>
2015
>
06/16/2015 (2)
Metadata
Thumbnails
Annotations
Entry Properties
Last modified
12/27/2018 2:15:58 PM
Creation date
12/27/2018 2:15:49 PM
Metadata
Fields
Template:
Meetings
Meeting Type
BCC Regular Meeting
Document Type
Agenda Packet
Meeting Date
06/16/2015
Meeting Body
Board of County Commissioners
Subject
Fire Station
Jump to thumbnail
< previous set
next set >
There are no annotations on this page.
Document management portal powered by Laserfiche WebLink 9 © 1998-2015
Laserfiche.
All rights reserved.
/
201
PDF
Print
Pages to print
Enter page numbers and/or page ranges separated by commas. For example, 1,3,5-12.
After downloading, print the document using a PDF reader (e.g. Adobe Reader).
View images
View plain text
Page 116 <br /> volatile organic compounds (MVOC)production, such as substrate,moisture conditions, <br /> temperature, oxygen concentration,age of the culture,and microbial species have been <br /> reported.66 The occurrence of MVOCs or odors is not a direct measure of the extent of <br /> microbial growth in a building because many factors affect indoor MVOC levels, as well as <br /> the occupants' susceptibility to odor. The odor thresholds vary from 10-7 to 101 ppm between <br /> individual MVOCs. <br /> Irritant effects are defined by dose,involve the mucus membranes of the eyes and upper <br /> and lower respiratory tracts, and are transient, disappearing when the exposure has decreased <br /> or ceased.68 The probability of irritating symptoms (i.e. irritation to the eyes, nose, and throat <br /> as well aseneral symptoms such as headache and dizziness)caused by microbial <br /> g <br /> contamination in buildings would increase considerably when concentrations of single VOCs <br /> are on the level of hundreds ofµg/m3 or mg/m3.69 However,there is a general lack of studies <br /> on dose-effect or dose-response relationships of irritation from single MVOC exposures and <br /> from MVOC mixtures.70 The concentrations of individual MVOCs in"problem"buildings <br /> have varied from a few ng/m3 to 1 mg/m3, and the same compounds have also been reported <br /> in"reference"areas and outdoor air. In general,the maximum reported levels of individual <br /> MVOCs are 0.1-10 1.tg/m3.71 <br /> Even if the presence of other MVOCs (and VOCs) in the air had a synergistic effect on the <br /> sensory irritation potency of individual MVOCs,MVOCs are not very important for indoor <br /> air problems. This conclusion is made because in general, exposure at indoor air <br /> concentrations is below levels needed for sensory irritation symptoms (i.e.eye and respiratory <br /> tract irritation)to occur in humans 72 The American Academy of Allergy, Asthma and <br /> Immunology concluded that"The occurrence of mold-related irritant effects from exposure to <br /> fungal irritants in nonoccupational settings are theoretically possible,although unlikely to <br /> occur in the general population given exposure and dose considerations."Furthermore,"Such <br /> irritant effects would produce transient symptoms-signs related to the mucus membranes of <br /> the eyes and upper and lower respiratory tracts but would not be expected to manifest in other <br /> organs or in a systemic fashion."73 <br /> VI. Conclusions <br /> Based on a review of the records provided to me in this matter and my general knowledge, <br /> training and experience in the field of toxicology, and specific knowledge of the effects of <br /> mold,mycotoxins, bacteria,and endotoxins,I opine that: <br /> 66 Korpi,A.et al.(2009).Microbial volatile organic compounds.Crit Rev Toxicol.39(2): 139-193. <br /> 67 Korpi,A.et al.(2009).loc. cit. <br /> 68 Bush,R.K.et al. (2006).loc. cit. <br /> 69 Pasanen,A.L.et al.(1998).Critical aspects on the significance of microbial volatile metabolites as indoor air <br /> pollutants.Environ Int.24(7):703-702. <br /> 70 Korpi,A.et al.(2009). loc. cit. <br /> 71 Korpi,A.et al. (2009).loc. cit. <br /> 72 Korpi,A.et al.(1999). Sensory Irritating Potency of Some Microbial Volatile Organic Compounds(MVOCs) <br /> and a Mixture of Five MVOCs.Arch Environ Health.54(5):347-352. <br /> 77 Bush,R.K.et al. (2006).loc. cit. <br /> 68 <br />
The URL can be used to link to this page
Your browser does not support the video tag.